Yunnan, located in southwestern China, harbors more than 19,000 higher plants, which represents the highest plant diversity in the country. However, plant diversity in Yunnan faces enormous threats today, including habitat destruction and fragmentation, environmental pollution, and over-exploitation of natural resources. Despite recent efforts to protect biodiversity, there are still thousands of threatened species, some of which have become extinct. We analyzed available data to gain a greater understanding of plant diversity and the status of plant conservation in Yunnan. We found that southern, southeastern, and northwestern Yunnan are hotspots of total species, endemic species, specimens, new species and threatened species, whereas southeastern Yunnan is a hotspot for plant species with extremely small populations. Moreover, we found that there are still conservation gaps and poorly protected areas in central, eastern, and northeastern Yunnan. We conclude that conservation of plant diversity in Yunnan requires modern field investigation, systematic research, the development of comprehensive databases, and government support. We recommend that conservationists pay more attention to building and improving functional protection systems and popularizing science.The transition from tropical to subtropical (warm temperate) evergreen forests is more clearly apparent in East Asia, from Nepal to the western Pacific coast, than elsewhere in the tropics. We review the nature of this transition and hypothesize the physical, ultimately climatic, factors that may maintain it, with a special focus on how the increasing instability and warming of climates will affect these forests. A primary climatic mediator of the transition is proposed, thereby offering a testable hypothesis for the climate-forest transition relationship. What is known of this transition is summarized in context of the primary climatic mediators of elevational zonation of forest formations in equatorial Asia to the tree line, in the Himalaya at the India-Indo-Burma northern tropical margin, and as both elevational and latitudinal zonation in southern China. Consequent secondary edaphic and other physical changes are described for the Himalaya, and hypothesized for southern China. The forest ecotones are seen to be primarily defined by tree floristic change, on which account changes in structure and physiognomy are determined. The montane tropical-subtropical transition in the Himalaya is narrow and observed to correlate with an as yet ill-defined frost line. A distinct tropical-subtropical transition forest is recognized in the southwest China mountains. There is a total change in canopy species at the Himalayan ecotone, but subcanopy tropical species persist along an elevational decline of c. 400 m. The latitudinal transition in South China is analogous, but here the tropical subcanopy component extends north over ten degrees latitude, albeit in decline. The tropical-subtropical transition is uniquely clear in East Asia because here alone a tropical wet summer-dry winter monsoon extends to 35° north latitude, encompassing the subtropical evergreen forest, whereas subtropical evergreen forests elsewhere exist under drier temperate summer climate regimes.The biodiversity of the Himalaya, Hengduan Mountains and Tibet, here collectively termed the Tibetan Region, is exceptional in a global context. To contextualize and understand the origins of this biotic richness, and its conservation value, we examine recent fossil finds and review progress in understanding the orogeny of the Tibetan Region. We examine the deep-time origins of monsoons affecting Asia, climate variation over different timescales, and the establishment of environmental niche heterogeneity linked to topographic development. The origins of the modern biodiversity were established in the Eocene, concurrent with the formation of pronounced topographic relief across the Tibetan Region. High (&gt;4 km) mountains to the north and south of what is now the Tibetan Plateau bounded a Paleogene central lowland ( less then 2.5 km) hosting moist subtropical vegetation influenced by an intensifying monsoon. In mid Miocene times, before the Himalaya reached their current elevation, sediment infilling and compreson biota argues for its conservation, and the importance of that biota is demonstrated through our insights into its long temporal gestation provided by fossil archives and information written in surviving genomes. These data sources are worthy of conservation in their own right, but for the living biotic inventory we need to ask what it is we want to conserve. Is it 1) individual taxa for their intrinsic properties, 2) their services in functioning ecosystems, or 3) their capacity to generate future new biodiversity? If 2 or 3 are our goal then landscape conservation at scale is required, and not just seed banks or botanical/zoological gardens.Human beings are not only a part of our planet's ecosystems, but also, they are massively overusing them. This makes ecosystem protection, including biodiversity preservation, vital for humanity's future. The speed and scale of the threat are unprecedented in human history. The long arch of evolution has been confronted with such a high level of human impact, that we are now facing the sixth mass extinction event, 66 million years after the last one. This threat heightens the imperative for bold human intervention. Our paper identifies three strategies for such an intervention. First, and possibly most challenging, human demand needs to be curbed so it fits within the bounds of what Earth's ecosystems can renew. Without meeting this quantitative goal, biodiversity preservation efforts will not be able to get scaled. Second, in the transition time, we must focus on those locations and areas where most biodiversity is concentrated. Such a focus on 'hotspots' will help safeguard the largest portion of biodiversity with least effort. https://www.selleckchem.com/CDK.html Third, to direct biodiversity preservation strategies, we need to much better document the existence and distribution of biodiversity around the globe. New information technologies could help with this critical effort. In conclusion, biodiversity preservation is no longer just a concern for specialized biologist but is becoming a societal necessity if humanity wants to have a stable future.